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Longevity Markers (Telomeres) When to expect changes: 1-3 years of consistent cycling Best supported by: In vitro telomerase activation, animal lifespan data, epidemiological mortality data with epithalamin Evidence quality: Low-moderate (strong in vitro, suggestive animal, weak human) Realistic outlook: This is a long-term bet on cellular biology

Abstract Early studies have shown that erythrocytes have caspase-3 and caspase-8 and are capable of dying through an apoptotic-like cell death triggered by Ca 2+ ionophores

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