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In these rare cases, sterile saline is used

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Weight loss goals should be personalized to each patient and weighed against risks of contributing to sarcopenia

[4] [5] The standard of care remains disease-modifying antirheumatic drugs (DMARDs), including conventional synthetic DMARDs like methotrexate as first-line therapy, with escalation to biological DMARDs or targeted synthetic DMARDs if disease activity remains inadequately controlled, following a treat-to-target approach

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