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Al-Mubarak, B
A diet that lowers melanin includes Glutathione sources (tomatoes, walnuts), vitamin C foods (bell peppers, oranges), and antioxidants (green tea, turmeric)
Model and physiological RS 2 and RSSR substrates are, for example, bis(2-hydroxyethyl)disulfide (HEDS) 1,3,12,14,30 , l-cystine 1,3 , redox-sensitive yellow or green fluorescent protein 2 (rxYFP or roGFP2) 14,15,31,32,33,34,35 , insulin 36,37 , collapsin response mediator protein 2 38,39 , the transcription factor OxyR 40 , 3-phosphoadenosine 5-phosphosulfate reductase (PR) 41,42 , methionine sulfoxide reductase (MSR) 34,43,44 , and ribonucleotide reductase (RNR) 2,34,45,46,47
Pre-fixation was done with 2.5% glutaraldehyde phosphate (0.1 M, pH 7.4) overnight at 4 C
Its directly involved in neutralizing free radicals, recycling antioxidants, and supporting liver detox pathways
All these factors contribute to cell damage which can reduce the lifespan of erythrocytes in blood (red cell senescence) since damaged erythrocytes are removed from circulation by the spleen
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