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Average weight loss at week 36 across all dose groups was 21.1%, with the 12mg cohort reaching 23.2%

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In addition to this, P4HA1 immune-modulatory role in cancer has been only recently analysed in different cancer types where its increase associated with worse cancer prognosis and lower overall survival, correlates with an immunosuppressive TME and reduced anti-tumoral response [24, 25, 64]

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