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Store them properly

Furthermore, the metabolic changes accompanying significant weight lossincluding alterations in hormone levels, body composition, and energy expendituremay temporarily affect energy levels as the body adapts to a new physiological state

Early clinical studies of advanced solid tumors, including hepatocellular carcinoma and colorectal cancer, have shown that when melatonin (usually 20 mg/day orally) is added to standard chemotherapy, patients experience better overall survival and lower toxicity from chemotherapy [30]

Well recommend a cadence based on your goals and, where relevant, your labs

In fact, it's pretty much tossing your money down the drain, or worse, it could backfire

10.1038/onc.2015.381 210 VanhoveK.DerveauxE.GraulusG