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These medications bind to GLP-1 receptors located throughout the body, including the pancreas, gastrointestinal tract, and importantly, the central nervous system

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Statements Author contributions LC contributed in collecting bibliography, in writing the manuscript, and in conceiving and creating the figures

Now, we don't know exactly how much overlap exists between heavy drinkers and GLP-1 users, but given that this group consumes thousands of extra liquid calories per week, I think it's reasonable to assume high rates of overweight and obesity in this group

Evidencing changes indicate the possibility of prebiotics having neuroprotective, stress-buffering effects through the modulation of the MGBA by restoring microbial homeostasis, changing neuroendocrine responses, or affecting gene expression in stress-related brain regions (Burokas et al., 2017)

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