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Human clinical trials of Motus reported about 10.4 percent average weight loss over six months, which is exceptional for an oral supplement and notable because most of the weight lost was fat rather than lean mass

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Renal or hepatic impairment calls for extra caution, since carnitine clears renally and methionine loads the liver

However, food intake did not differ significantly between the two groups (Figure 1B)

Pancreatic Safety: At the core of the apprehensions surrounding GLP-1 agonists sits pancreatic safety