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94 Moreover, SLC1A3 is mainly expressed in brain tissue, and its high expressions in some solid tumors, such as clear cell renal cell carcinoma, papillary renal cell carcinoma, hepatocellular carcinoma and gastric adenocarcinoma, may make SLC1A3 inhibitors a solution to ASNase resistance

10.3389/fimmu.2019.01395 175 YouD

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Different peptides behave differently inside the body, and factors such as metabolism, dosage, injection method, body composition, and treatment goals all influence how long a peptide remains active or detectable

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In other embodiments, a formulation or composition disclosed herein is applied via microcathethers implanted into the patient, and in yet further embodiments a composition disclosed herein is administered via a pump device onto or near the round window membrane