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In our approach based on the concentration-effect relationships, we did not account for all possible confounding factors known to influence lactate clearance

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Upregulated expression of both eNOS and iNOS (Fig

Effectiveness of saxagliptin tablets was not demonstrated in a 26-week, placebo-controlled, double-blind randomized clinical trial with a 26-week safety extension (NCT03199053) in 164 pediatric patients aged 10 to 17 years with inadequately controlled type 2 diabetes mellitus In the seven, double-blind, controlled clinical safety and efficacy trials of saxagliptin, a total of 4751 (42%) of the 11301 patients randomized to saxagliptin were 65 years and over, and 1210 (10.7%) were 75 years and over