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In the case of varicella-zoster virus, interaction with the cellular receptor causes a structural change in the proteins on the surface of the virus, which promotes fusion between the membranes of the virus and cell

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One study has shown that a factor V level less than 10% of normal indicated a poor prognosis (91% mortality), whereas a ratio of factor VIII to factor V of less than 30 indicated a good prognosis (100% survival).[50] The respiratory formulation can also be diluted and filter sterilized by a hospital pharmacist for IV use

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