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This work was supported in part by the Koch Institute Support (core) grant (no
AGEs accumulate in myocardial tissue and create covalent bonds with substances like collagen, causing an increase in collagen formation, aggravated myocardial fibrosis, and promotion of aortic sclerosis
These investigations should include assessments of skin permeability, drug release kinetics, and compatibility [358]
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Furthermore, for patients experiencing age-related physical decline, MTC provides comprehensive hormone replacement therapy to address the root causes of fatigue and tissue degradation safely
