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Knockdown of GCH1 significantly activated ferritin autophagy upon erastin treatment, which was reversed by using an autophagy inhibitor

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Thus, 22q11.2 deletion, which is related to ASD, is associated with both mitochondrial and synaptic abnormalities

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This review highlights recent structural insights into gating and pharmacological regulation of KARs, offering deeper understanding of their roles in synaptic transmission and neuronal signaling

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