Furthermore, a frustrating feeling arises that the medication simply stopped working completely for the individual patient
For ongoing obesity management, patients should discuss alternative options with their GP or specialist, which may include other pharmacological agents (such as orlistat), behavioural interventions, or referral for bariatric surgery assessment in appropriate cases
The broader opportunity may lie in how these therapies reshape the ecosystem around weight management, nutrition, and preventive healthcare
doi: 10.1039/c7sc04416j
To this regard, it has been reported that the time to conceive is longer in women with body mass index (BMI) superior to 25 kg/m 2 or inferior to 19 kg/m 2 , and that both overweight and obesity are significantly related with reduced pregnancy rate, increased supplies of gonadotrophins and higher miscarriage rate
This dual mechanism distinguishes Mounjaro from exendin-4-based therapies, offering enhanced glycaemic control and weight reduction in type 2 diabetes
