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Open field test (OFT) The OFT assesses spontaneous locomotor activity and exploratory behavior in experimental animals

TRPV4 activation by A in hippocampal cells can increase calcium influx, leading to more oxidative stress and cell death, worsening AD [83]

PubMed Seiwerth, S., Rucman, R., Turkovic, B., Sever, M., Klicek, R., Radic, B., Drmic, D., Stupnisek, M., Misic, M., Vuletic, L.B., & Sikiric, P

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Similarly, it has been observed that KRAS mutation induces activation of the glutamine metabolism pathway in pancreatic cancer by enhancing the expression of pivotal enzymes responsible for glutamine degradation [92]

A study utilizing a national database found that individuals treated with GLP-1 receptor agonists had a significantly lower risk of developing glaucoma compared to those who were not on these medications