Wegovy contains the same main ingredient as Ozempic, semaglutide, and is FDA-approved for weight loss in people with obesity or who are overweight with at least one weight-related condition
The drug is being developed by Eli Lilly and Company, which has announced plans to progress retatrutide into Phase 3 clinical trials across multiple indications, including obesity, type 2 diabetes, and liver disease
Both classes are examined for effects on hepatic fat, lipid profiles, blood pressure and markers of insulin sensitivity
The key principle is managing the underlying condition, not tapering the drug
Perreault, L., et al
Moderate-intensity exercise appears particularly effective, with studies showing increased GLP-1 secretion in people with type 2 diabetes following exercise interventions