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Transmission electron microscopy shows that the mitochondria of dorsal horn neurons of the spinal cord exhibit characteristic changes of ferroptosis, such as mitochondrial shrinkage and increased mitochondrial inner membrane density

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Higher levels of oxidized glutathione (GSSG) were observed, indicating increased oxidative stress in children with ASD

This crosstalk between hydrogel-mediated local immune activation and systemic antitumor immunity forms the basis of a powerful therapeutic synergy, where localized hydrogel delivery serves as an immune-priming depot that amplifies the effects of systemic immunotherapies

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