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The adipocyte secretes over 50 cytokines and hormones that both enhance and suppress inflammation, secretes extracellular matrix proteins that impact inflammation, produces and releases toxic lipids that aggravate inflammation, and, more recently, was shown to present antigen to activate CD4+ T cells

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Full Answer: GLP-1 agonists like semaglutide and tirzepatide primarily reduce body weight by suppressing appetite and improving insulin signaling

Clinical data shows approximately 5 to 7 percent body weight reduction by this point

With its two activating groups, the benzene ring is highly reactive towards electrophilic aromatic substitution