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Synthesis of potent and selective inhibitors of aldo-keto reductase 1B10 and their efficacy against proliferation, metastasis, and cisplatin resistance of lung cancer cells

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The combination leads to endothelial dysfunction, cholesterol deposition, inflammation, and finally, calcification.[ref] Oxidized phospholipids are primarily polyunsaturated fatty acids that are oxidized due to ROS, infections, or apoptosis

Cancer Cell 17 , 135147 (2010)

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