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We reviewed publicly available policies, ingredient disclosures, company documentation, and general industry context to inform this analysis

Previous non-responders or partial responders to Semaglutide

Can lifestyle also help to support GLP-1 levels

Certain groups of people should not use Semaglutide GLP-1 or should use it with caution under healthcare professional supervision

One datapoint in vehicle group was excluded due to the running wheel got stuck between day -1 to day 0

Christoffersen B, Sanchez-Delgado G, John LM, Ryan DH, Raun K, Ravussin E (2022) Beyond appetite regulation: targeting energy expenditure, fat oxidation, and lean mass preservation for sustainable weight loss