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GLP-1 is typically prescribed for adults with a BMI greater than 30, or a BMI of 27 or higher with one or more weight-related medical conditions, such as type 2 diabetes, high cholesterol, or high blood pressure

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Results at 72 weeks were striking: 5mg dose: 15.0% average weight loss 10mg dose: 19.5% average weight loss 15mg dose: 20.9% average weight loss Placebo: 3.1% average weight loss At the highest dose, 36.2% of participants lost 25% or more of their body weight

PMID: 18541709

The studys primary endpoint was the percentage change in body weight from baseline to 24 weeks of therapy