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The experiments were conducted by placing the mice in one of four 50 50 50 cm arenas immediately after compound administration, allowing their locomotion to be monitored by a ceiling-mounted Logitech C920 Pro camera (1,080 1,080 px, 30 fps, Logitech software)
10.1203/00006450-199610000-00018 73 TrachtmanH.SchwobN.MaesakaJ.ValderramaE
Appetite suppression became clearer and early fat loss of 2-4% body weight was reported
In the case of iron overload, the loss of SLC7A11 contributes to ferroptosis-related liver injury ( function, triggering ferroptosis in cancer cells derived from the liver, kidney, and lung ( in vivo , whereas SLC7A11 / embryonic fibroblasts underwent cell death in routine culture medium in vitro but could proliferate normally in the presence of 2-mercaptoethanol (2ME), N-acetyl cysteine (NAC), or vitamin E ( Inhibition of GSH synthesis triggers ferroptosis