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Differentially expressed genes (DEGs) between OA and normal cartilage tissues in the GSE98918 dataset were identified using the limma package 21 , with the significance threshold set at |logFC| 0.5 and adjusted p -value 0.8 indicates good diagnostic performance 24

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J Appl Physiol 1993;75(6):241924

The skin, subcutaneous tissue, and fascia were sequentially incised, and a pencil-tipped guide rod was inserted and placed on the surface of the intervertebral space