More commonly, it results from rapid weight loss placing temporary strain on muscles and spinal structures that had adapted to supporting extra body weight
194 GLP-1 also acts directly on the liver, inhibiting glycogenolysis, promoting glycogen synthesis, and regulating the expression of lipid metabolism-associated genes, thereby reducing hepatic fat accumulation and improving glucose and lipid homeostasis along the gutliver axis
Athletes may use these substances outside competition only within governing body guidelines
Evidence shows that surgery provides added, durable benefits beyond medications alone. Prior research showed bariatric surgeries decreased from 2022 to 2023, while GLP-1 use grew by 132.6% during that time, though surgery may present certain benefits, such as cost-effectiveness, over the anti-obesity medications
For example, the process with 1st Optimal, a Maximus competitor, involved labs, a review by a physicians assistant or nurse practitioner, a call with that PA or NP, then a follow-up conference call to loop your MD into the picture
Drinking water and eating balanced meals can help manage these symptoms