Modulation of gamma-aminobutyric acid (GABA)related signaling has been observed in preclinical models, a mechanism that may contribute to reduced anxiety-like behaviors and enhanced neural stability (27)
However, using variants that do not dimerize, it has been recently described that homodimer formation of GCL is not required for enzyme activation (Yang et al., 2019)
These processes include neural cell proliferation and differentiation, cortical lamination, and neuronal migration
10.1016/j.immuni.2019.12.018 86 GaoM.MonianP.JiangX
Immunol Lett (2020) 225:5763
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