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If side effects become limiting, the dose can be reduced or adjustments can be made to meal timing, hydration, or accompanying medications

Tirzepatide stimulated insulin secretion in a concentration-dependent manner (0100 nM) in control islets (Fig

METH stimulates the release of excess glutamate from neurons while inhibiting its uptake by astrocytes, leading to the overactivation of NMDARs (Northrop et al., 2011)

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