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The Johnsons score, an indicator of spermatogenesis function, also significantly improved in the FOXO4-DRI-treated aged group

Metformin treatment throughout pregnancy in women with PCOS does not cause significant adverse effects such as fetal growth retardation or intrauterine death (Lautatzis et al., 2013)

doi: 10.1155/2015/247426 140 FiggettWADeliyantiDFairfaxKAQuahPSWilkinson-BerkaJLMackayF

Potential renal stress markers reported in rodent studies at higher doses