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Furthermore, oxidative stress impairs the antioxidant defense system by decreasing expression of key enzymes such as GSH, catalase, superoxide dismutase and GPX, thus accelerating ferroptosis (56,57)

Suppression of AMP-activated protein kinase reverses osteoprotegerin-induced inhibition of osteoclast differentiation by reducing autophagy

Esta regulacin es bidireccional: el pptido puede aumentar o disminuir la produccin de NO segn el contexto patolgico, contribuyendo as a la proteccin vascular y a la reduccin de la inflamacin

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Immunity 39 (5), 976985

"Even the approved ones have real complications," said Dr