Our study revealed negative regulation of LRP1-binding proteins (e.g., TIMP2, FN1, SERPINE2, MMP2, DCN, C1S, C1R, and CTSD) in chondrocytes exposed to H 2 O 2 , corroborating findings from LRP1 knockdown models [85], except for PSAP, which was downregulated in our study but upregulated in LRP1 knockdown models
Cytostatic agents, particularly platinum-based drugs such as topotecan and cisplatin, have been linked to the induction of eryptosis, thereby worsening anemia [392, 393]
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FDA Halts Sale of Off-Brand Ozempic and Other GLP-1 Drugs
This debate is especially relevant for India as reports suggest large sales and adoption of GLP-1 among affluent urban consumers across Mumbai, Delhi, and Bengaluru
Physiol Mol Biol Plants 27:24072420