Orforglipron treatment led to a significant reduction in body weight compared with controls
10,17 GLP-1 receptor stimulation in the arcuate nucleus also improves glycemic control independent of feeding behavior
Its not hard to understand why sticking with this regime is challenging a large minority of patients report unpleasant side effects such as nausea and vomiting, and some experience additional side effects such as injection-site reactions, infections, heart burn, and headaches
Many GLP-1 promotions target women who are not medically obese or diabetic
McLean BA, Wong CK, Campbell JE, Hodson DJ, Trapp S, Drucker DJ
Siegel says the current cost of these medications is definitely a barrier and that often, patients who could benefit from a GLP-1 are on other expensive medications as well