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While at-home administration is possible with a prescription and guidance from a qualified medical professional, self-medicating comes with substantial risks

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In sponsor trials, materials are pre-prepared, not lyophilized vials handled by patients

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Cartilage loss & OA progression : Studies published in journals like Radiology (2017) and JAMA (2017) have shown repeated intra-articular cortisone to accelerate cartilage loss and faster osteoarthritis progression, even if pain improves short term