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LR3 IGF-1 has a reduced affinity for IGFBPs, longer half-life, and higher biological potency compared to wildtype IGF-1

There are also newer, broad-spectrum medications that cover all these groups in a single product

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Compounds marketed as dual or triple agonists, such as tirzepatide, act at combinations of the GLP-1, GIP, and glucagon receptors rather than at any third GLP receptor

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Ovulation Induction: Typically, a single 5000 IU injection is administered approximately 36 hours before planned ovulation or insemination