the separation and regeneration results are more consistent, and the service life of the resin is extended
Medical conditions affecting absorption warrant particular attention : Pernicious anaemia : an autoimmune condition destroying gastric parietal cells, requiring lifelong B12 injections Gastrointestinal surgery : particularly gastric bypass, gastrectomy, or terminal ileum resection Inflammatory bowel disease : Crohn's disease affecting the terminal ileum impairs absorption Coeliac disease : untreated disease damages the small intestine, reducing B12 uptake Medication use : long-term metformin therapy (MHRA safety alert) or nitrous oxide exposure Symptoms suggesting possible B12 deficiency include : persistent fatigue, weakness, paraesthesia (pins and needles) in hands or feet, glossitis (sore, red tongue), mood changes, memory problems, or unexplained anaemia
"In concrete terms, we advise these patients to guard their physical limits and not to exceed them," said Brent Appelman, a researcher at Amsterdam UMC
Easy-to-use liquid formula includes dropper for accurate dosing
Experimental and Therapeutic Medicine
Lopes, R
