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[DOI] [PMC free article] [PubMed] [Google Scholar] 145.Mann M.C., Hemmelgarn B.R., Exner D.V., Hanley D.A., Turin T.C., Wheeler D.C., Sola D.Y., Ellis L., Ahmed S.B

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Nuclear factor-erythroid 2-related factor 2 (Nrf2) is a key transcription factor upregulating the antioxidant response element (ARE)-mediated expression of antioxidant and detoxifying enzymes, and the Nrf2-antioxidant pathway is critical in host defense against acute lung injury (ALI) 24

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