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Additionally, increased paracellular permeability (Keaney and Campbell, 2015), and increased immune cell trafficking, including infiltrating leukocytes, can exacerbate inflammatory responses, leading to increased neuronal damage and injury (Huang et al., 2006)

Robinson K, Mayer EL, Miller DP, Green R, van Lente F, Gupta A, Kottke-Marchant K, Savon SR, Selhub J, Nissen SE, Kutner M, Topol EJ, and Jacobsen DW (1995)

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