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In B12 deficiency, DNA synthesis in red blood cell precursors (erythroblasts) can be impaired, preventing the normal maturation and division of these cells, resulting in larger-than-normal red blood cells

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 "Vitamin B12: Fact Sheet for Health Professionals"

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Obwohl diese Nebenwirkungen sehr selten sind, fhrt die breite Anwendung von Metamizol zwangslufig zu einer relevanten Zahl betroffener Patienten

While most of these studies are preliminary, they have shown promising results