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The ability of mitochondria to rapidly adapt to stress, including stress imposed by antimetabolites such as 5FU, means that they have significant potential to dictate therapeutic responses 11

If a designer builds a device that requires a strict, constant 3.7V to operate, the device will fail as soon as the battery drops below that threshold, leaving nearly 50% of the batterys capacity unused

The Post piece quoted a sentence from my 2019 book Anti-Diet that I really should have written with more subtlety: Most chronic diseases blamed on weight can most likely be explained by other phenomena, such as weight stigma and weight cycling. As I shared here several weeks ago: Overall I still stand behind my work in Anti-Diet and Food Psychits based on solid scientific evidence and informed by my clinical experience and interviews with people whose perspectives are invaluablebut I wish Id been more nuanced in my delivery

The issue is exacerbated by evolutionary defences such as RNases, toll-like receptors, and the rapid elimination by the kidneys and liver, which further diminish bioavailability

A pain pump called a patient-controlled analgesia (PCA) device

Possible side effects include nausea, vomiting, diarrhoea, and constipation