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Diabetes, Obesity & Metabolism, 20 ,
Additionally, by stimulating insulin secretion and suppressing glucagon release, Ozempic supports balanced blood sugar levels, further contributing to overall metabolic health
Comparisons With Other Diabetes Therapies Putting GLP1s in context with other antidiabetic agents offers additional insights: Thiazolidinediones (TZDs) are associated with increased fracture risk, especially in women SGLT2 inhibitors have raised concerns in some trials, particularly canagliflozin DPP-4 inhibitors appear largely neutral regarding skeletal effects Against this backdrop, GLP1s may have a neutral or possibly safer profile, though the data are not conclusive
Reduced NGF is associated with Alzheimers disease, Parkinsons disease, and age-related cognitive decline
