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10.1002/mrd.22930 23

Denat L, Kadekaro AL, Marrot L, Leachman SA, Abdel-Malek ZA

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312,313,314,315 Maintaining this calcium homeostasis is fundamental to calcium signaling, and disruption in cytosolic calcium concentration gradients, as well as abnormalities in calcium signaling pathways, may lead to neurodegenerative diseases such as AD and Parkinsons disease (PD), cardiovascular diseases, and metabolic disorders