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It describes men with documented hypogonadism plus obesity or overweight status who have already failed single-agent weight management, with selection depending on age, comorbidities, cardiovascular status and metabolic resilience

Adam Mendelsohn, CEO of Vivani Medical, is betting that tiny, long-acting implants can fix that

The drug performed better on all secondary endpoints as well, including a greater percentage of people losing at least 15% of their weight (roughly a third of those on the highest dose achieved this)

Expect FDA to require specific NAION warnings, more explicit gastroparesis disclosures, and possibly black box warnings for the most serious risks

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With that criterion, cases of mixed hepatitis described in the literature were included in the cholestatic hepatitis cohort