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[126] demonstrated that STAT3 signaling activated the expression of IDO, a major inducer of the immunosuppressive milieu, without the need for binding of STAT3 protein to the promoter of IDO gene in human MDSCs

Angiotensin III (Arg-Val-Tyr-Ile-His-Pro-Phe) binds at the AT 1 but primarily at the AT 2 receptor subtype and modulates cell proliferation, cell differentiation, and apoptosis

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doi: 10.1016/J.RMED.2005.10.022 76 WoodLGGibsonPGGargMLBlakeRJGarcia-CaraballoS

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