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4, 5, and 6 are prepared with the appropriate amounts of a JNK inhibitor, such as any one of the JNK inhibitors described herein, and medium chain triglyceride (CRODAMOL, GTCC-LQ-(MV), PhEur) as shown in the below table (Table D).Formulations The formulations are prepared by adding the target weight percentage of the JNK inhibitor to the appropriate amount of medium chain triglyceride

S is calculated from estradiol by formula (2)

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L-glutathione reduced (GSH) is the active form of glutathione, a naturally occurring antioxidant in our bodies

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Timing Considerations Timing considerations favor consistency over specific time selection