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Undoubtedly, eukaryotic cells have complex system of enzymatic antioxidants such as superoxide dismutase-1, 2 and 3 (SODs), catalase, glutathione peroxidase (GPx)

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Consistently, DMF significantly induced the expression of antioxidant proteins such as Nqo1 and Gpx4, which are critical for detoxification reaction and GSH utilization (Fig

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