The ESSENCE data may represent key findings for patients in the treatment of MASH, which is estimated to affect about one in 20 adults in the U.S., Sanyal said
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Of interest, in people treated with exenatide or liraglutide in combination with insulin, discontinuation with insulin was associated with a greater weight reduction and a lesser effect on HbA 1c , compared with continuing with insulin [67]
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The association remained significant after matching for key risk factors, such as age, race, ethnicity, BMI, breast density, and diabetes status, suggesting the findings were not solely due to differences between groups