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Lupi et al., (2010), tested the effects of acute (45 min) or prolonged (2 days) exposure to GLP-1 or GIP, alone or in combination on human pancreatic islets, that were obtained from non-diabetic and type 2 diabetic donors

In contrast, obesity may be associated with increased circulating prolactin levels, which are potentially mediated by adipose tissue expansion, enhanced aromatase-dependent estrogen production, and chronic low-grade systemic inflammation

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Am J Pathol (2011) 179(5):245463