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24-h urine samples were collected from GD 16.5 to GD 17.5, and on GD 17.5, pregnant rats were euthanized by pentobarbital sodium overdose for placental tissues, peripheral blood, kidney, and fetuses

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Following the whole-organ imaging, the brain was further sectioned via sagittal slices (2-3mm thickness) into two and then four pieces to better visualize the brain regions that semaglutide is known to interact with