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MOTS-c is classified as a mitochondrial-encoded peptide and is commonly explored in studies examining cellular metabolism, stress-response signaling, and mitochondrial communication mechanisms

The x-axis represents CV values, and the y-axis indicates the proportion of substances with less than the corresponding CV value relative to the total number of substances

Any use outside of formally approved clinical trials falls outside the regulatory framework that governs medicines safety in the UK, meaning that individuals who obtain and use retatrutide independently do so without the quality assurance, standardised dosing oversight, and pharmacovigilance protections afforded by licensed medicines

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J Inherit Metab Dis 37:783789

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