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While these side effects can be mild, they can be very bothersome to some people

EGFR and c-MET have in common similar downstream pathways: MAPK (RAS/Rapidly accelerating fibrosarcoma (RAF)/ MAP kinase kinases (MEK)/ERK) and PI3K/AKT/mechanistic target of rapamycin (mTOR)

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Mechanisms: How GLP-1 Therapy Influences Gallstone Formation One major contributor is reduced gallbladder motility

Additionally, in basic research, future studies could establish mouse models of obesity and diabetes and compare them with normal mice to exclude the interference of metabolic factors

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