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In addition, glutathione helps maintain the activity of other important antioxidants, including Vitamins C and E , allowing them to continue performing their protective functions

In septic lung injury, elevated lactate levels exacerbate alveolar epithelial cell ferroptosis through lactylated histone H3 lysine 18 (H3K18la)-mediated upregulation of METTL3, which enhances m6A modification of ACSL4, ultimately contributing to the development of acute respiratory distress syndrome (82)

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