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Jastreboff AM, le Roux CW, Stefanski A, Aronne LJ, Halpern B, Wharton S

Polymeric nanoparticles, especially those derived from PLGA (poly(lactic-co-glycolic acid)), have been used to prepare long-acting formulations of GLP-1 that can extend the release period to weeks with a single dose, reducing injection frequency and improving patient adherence [33]

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We confirmed these observations in human islets

References Woodward, M

Transdermal delivery of proteins