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To achieve targeted delivery of GLP-1RAs to affected joints, we developed a cartilage-targeting nanoparticle system (GLP-1RAs@NPs-WYRGRL) and integrated it into a methacrylated hyaluronic acid-based microneedle patch (MNs/GLP-1RAs@NPs-WYRGRL)

And just like a medication that never reaches the bloodstream cannot produce results, a peptide that degrades in stomach acid before absorption cannot deliver on its potential

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Unlike full HGH, AOD-9604 lacks growth-promoting or diabetogenic effects but retains the fat-burning activity attributed to HGH's C-terminus